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Vanja Karamatic Crew on Muck Rack

Vanja Karamatic Crew

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Articles

Homozygosity for a novel A4GALT allele resulting in the rare p phenotype in an Indian blood donor

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By Louise Tilley, Transplant Bristol, Vanja Karamatic Crew, Amy Tearle
| Wiley Online Library Verified
Individuals with the rare p phenotype have red cells lacking P, P1 and Pk antigens and make clinically significant anti-PP1Pk. The phenotype arises from inactivating mutations in A4GALT, which encodes the enzyme responsible for production of P1 and Pk. We present results from serological and molecular investigations of a case of anti-PP1Pk with a novel molecular background of the p phenotype.
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