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Varona Baranda on Muck Rack

Varona Baranda

As seen in: Frontiers
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Articles

CTCF deletion alters the pluripotency and DNA methylation profile of human iPSCs

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By Elsafi Mabrouk, Tetsuya S. Tanaka, Shin-ichi Horike, Varona Baranda
| Frontiers
1 Introduction Differentiation of induced pluripotent stem cells (iPSCs) toward specific cell types remains a challenge and the underlying mechanisms that control cell-fate decisions are so far hardly understood. During the reprogramming of somatic cells into iPSCs and their lineage-specific differentiation, extensive epigenetic remodeling occurs.
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