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Vasilios T Garyfallou on Muck Rack

Vasilios T Garyfallou

As seen in: Journal of Molecular Endocrinology
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Articles

Gene expression profiling of the SCN in young and old rhesus macaques

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By Dominique Eghlidi, Universidad de Valparaíso, Donald Brown, Vasilios T Garyfallou
| Journal of Molecular Endocrinology Verified
In mammals, the suprachiasmatic nucleus (SCN) is the location of a master circadian pacemaker. It receives photic signals from the environment via the retinal hypothalamic tract, which play a key role in synchronizing the body’s endogenously generated circadian rhythms with the 24-h rhythm of the environment. Therefore, it is plausible that age-related changes within the SCN contribute to the etiology of perturbed activity–rest cycles that become prevalent in humans during aging.
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Age-associated gene expression changes in the arcuate nucleus of male rhesus macaques

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By Dominique Eghlidi, Steven Kohama, Vasilios T Garyfallou, Henryk F Urbanski
| Journal of Molecular Endocrinology Verified
The hypothalamic arcuate nucleus (ARC) represents a major component of the neuroendocrine reproductive axis and plays an important role in controlling the onset of puberty as well as age-associated reproductive senescence. Although significant gene expression changes have been observed in the ARC during sexual maturation, it is unclear what changes occur during aging, especially in males.
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