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Vasily Ogryzko on Muck Rack

Vasily Ogryzko

As seen in: BioRxiv
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Articles

PKA prevents resection of DNA double strand breaks and favor non-homologous end-joining

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By Bernard Lopez, Houaria Khater-Sellou, Indiana Magdalou, Vasily Ogryzko
| BioRxiv
Abstract Genome rearrangement is a hallmark of cancer and ageing. DNA double-strand breaks (DSBs) are highly toxic lesions that can generate genome rearrangements. Several pathways compete for DSB repair, and selection of the appropriate repair process is decisive for genetic stability.
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