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Lurbinectedin in treating CNS metastases from small cell neuroendocrine prostate cancer—a case report
Abstract Background: De novo neuroendocrine prostate cancer is an aggressive, androgen receptor-independent subtype of prostate cancer with poor prognosis. Central nervous system (CNS) metastases from de novo neuroendocrine prostate tumors are rare, and evidence guiding treatment is limited. Lurbinectedin, approved for small cell lung cancer (SCLC), has shown activity in neuroendocrine tumors, though CNS-specific data remain sparse.
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