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Veluchamy A. Barathi on Muck Rack

Veluchamy A. Barathi

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Biomolecules | Free Full-Text | Intravitreal Neuroglobin Mitigates Primate Experimental Glaucomatous Structural Damage in Association with Reduced Optic Nerve Microglial and Complement 3-Astrocyte Activation

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By Myoe N. Lynn, Candice Ho, Rehena Sultana, Veluchamy A. Barathi
| MDPI
4. Discussion In this study, we investigated the effects of exogenous IVT-Ngb in a primate model of EG by studying the IOP-mediated structural changes based on OCT measurements as well as the astroglia and microglia of the optic nerve. We also evaluated the ocular safety profile of IVT-Ngb. We recently reported the ONH OCT changes induced by the microbead approach to IOP elevation in primates and, thus, used this primate model of EG and similar OCT protocols for this study [30].
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