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Venkatareddy Edhara

As seen in: Royal Society of Chemistry
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Entry to 4,5-Fused Coumarin frameworks via Radical-Promoted Alkylative Intramolecular C5-Annulation

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By Raji reddy Chada, Ankita Kumari, Amol Patil, Venkatareddy Edhara
| Royal Society of Chemistry Verified
Entry to 4,5-Fused Coumarin frameworks via Radical-Promoted Alkylative Intramolecular C5-Annulation An unprecedented radical-promoted strategy involving domino alkylation/intramolecular C5-annulation of N-acryloyl-4-amino coumarin has been devised for the assembly of 4,5-fused coumarin scaffolds. This protocol employs silver-catalyzed oxidative decarboxylation for the generation of alkyl radicals from carboxylic acids as radical precursors.
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