Venkatesh Teja Banala

Development of putrescine anchored nano-crystalsomes bearing doxorubicin and oleanolic acid: deciphering their role in inhibiting metastatic breast cancer† Ravi Prakash Shukla,a Sandeep Urandur,a Venkatesh Teja Banala,a Disha Marwaha,a Shalini Gautam,a Nikhil Rai,a Neha Singh,a Pratiksha Tiwari,a Prashant Shukla a and Prabhat Ranjan Mishra *a Author affiliations * Corresponding authors a Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute Lucknow, India...

Development of Putrescine anchored nano-crystalsomes bearing Doxorubicin and Oleanolic acid- Deciphering its role in inhibiting metastatic breast cancer Angiogenesis driven tumor initiation and progression calls for a targeted therapy. Moreover, the inclusion of combined chemotherapy supplement the therapy acting on cause of concern. In the line of context, we envisagedto develop a targeted crystalosomes delineating the tumor cells against the normal cells.

Multifunctional hybrid nanoconstructs facilitate intracellular localization of doxorubicin and genistein to enhance apoptotic and anti-angiogenic efficacy in breast adenocarcinoma† The progressive development of tumors leading to angiogenesis marks the advancement of cancer which requires specific targeted treatment preferably with combination chemotherapy.