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Vereena Salib on Muck Rack

Vereena Salib

As seen in: BioRxiv
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Articles

Pathogenic BRCA1 DBD variants exhibit altered DNA binding affinities and susceptibility to menadione

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By Emma Cismas, Kaitlin Lowran, Esme Lowry, Vereena Salib
| BioRxiv
Abstract Breast Cancer Susceptibility Gene 1 (BRCA1) codes for a DNA repair protein that facilitates the repair of double-stranded DNA breaks (DSBs) in human cells through the homologous recombination (HR) pathway. Mutations of BRCA1 are highly associated with breast cancer; however, many variants remain unclassified with unknown cellular phenotypes.
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