Véronique Michel

Abstract Glacial terminations stand out for their high rates of sea-level rise, particularly during meltwater pulses. Termination IV (T-IV; ~340,000 years before present) is a prominent example, with sea level rising at up to ~5 m per century. Due to sparse absolute age constraints on marine records, the causes for the high rates of sea-level rise at T-IV remain elusive. In this work, we provide a speleothem chronology from northern Italy, which we transpose to North Atlantic marine records.

The ENALEPSY trial evaluated the efficacy of intravenous naloxone to reduce the severity of post-ictal complications after focal to bilateral tonic–clonic seizures. Naloxone did not improve the delay of recovery of SpO2 ≥ 90% or the desaturation nadir. The time to mobility recovery was significantly shorter in the NLX group when compared to historical control. Impact of these results on SUDEP prevention will require additional studies.

Abstract The first “Out of Africa” migrations represent a seminal event in the history of humankind. At the gates of Europe, the first appearance of Hominins is recorded in Georgia, 1.8 million years ago (Ma); however, the picture of migration across the continent remains incomplete. Vallonnet Cave (France) is a Lower Paleolithic prehistoric site with traces of hominin activities including lithic remains and cut-marks on mammal bones.