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Vesna Barros on Muck Rack

Vesna Barros

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Articles

Proteomic risk score for early prediction of kidney disease progression in individuals with APOL1 high-risk genotypes

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By Chenyu Li, Shola Richards, Ghazal Quinn, Amin Abedini, Minyan Zhu, Tanya verma, Samer Mohandes, Rebecca Pitts, Xiazi Qiu, Taehwan Shin, Joseph Loureiro, Nancy Finkel, Aditya Surapaneni, Josef Coresh, Morgan E. Grams, Hongzhe Li, Anurag Verma, Marylyn D. Ritchie, Daniel Rader, Penn Medicine Biobank, William Dietrich, Lori L. Jennings, Katalin Susztak, Vesna Barros, Anil Karihaloo
| Nature Verified
Abstract Individuals of African ancestry carrying APOL1 (apolipoprotein L1) high-risk genotypes face a markedly increased risk of kidney failure, yet tools to identify those individuals likely to progress to chronic kidney disease are lacking. Here we profiled plasma proteomes of 851 Penn Medicine BioBank participants of African ancestry (285 males and 566 females) with APOL1 high-risk genotypes and preserved estimated glomerular filtration rate (eGFR) (≥60 ml min−1 1.73 m−2).
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