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Vignesh Bose Nathan

As seen in: BioRxiv
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Articles

Understanding disease-associated metabolic changes in human colon epithelial cells using iColonEpithelium metabolic reconstruction

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By Boyu Jiang, Nick Quinn-Bohmann, Christian Diener, Vignesh Bose Nathan
| BioRxiv
Abstract The colon epithelium plays a key role in the host-microbiome interactions, allowing uptake of various nutrients and driving important metabolic processes. To unravel detailed metabolic activities in the human colon epithelium, our present study focuses on the generation of the first cell-type specific genome-scale metabolic model (GEM) of human colonic epithelial cells, named iColonEpithelium.
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