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Vigneshwaran Velligiri on Muck Rack

Vigneshwaran Velligiri

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Articles

Condensation of cGAS induced by Tyr 242 phosphorylation and interaction with MYL6 mediates vascular innate immunity in the lung

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By Bhagwati Joshi, Jagdish Joshi, Zahid Akhter, Peter T Toth, Tejabhiram Yadavalli, Josh Thompson Verified, Somenath Banerjee, Deepak Shukla, Vadim Gaponenko, Yulia A. Komarova, Dolly Mehta, Kyle A. Starost, Vigneshwaran Velligiri
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary The cytosolic double-stranded DNA (dsDNA) sensor cGAS stimulates type I interferon production as part of the innate immune response to infection. Dysregulated cGAS activation in response to pathogens leads to inflammation and acute lung injury. Joshi et al.
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