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Vijay Sharma on Muck Rack

Vijay Sharma

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Articles

Structural basis for oligoclonal T cell recognition of a shared NRAS cancer neoantigen

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By Vijay Sharma, D. Gallagher, Shayana Saravanakumar, Pragya Parijat Singh, Brian Pierce, Roy A. Mariuzza
| Cell Press Verified
Keywords T cell receptor cancer neoantigen oncogene MHC X-ray crystallography Alphafold NRAS mutations Introduction Adoptive cell therapy (ACT) with tumor-specific T cells can promote durable regression of diverse cancers, including metastatic melanoma, colon, cervix, bile duct, and breast cancers.1,2,3,4,5,6 The therapeutic effect of these ex vivo-expanded tumor-infiltrating lymphocytes (TILs) is mediated primarily by CD8+ cytotoxic T cells,7 with an additional contribution from CD4+ T...
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International Journal For Multidisciplinary Research

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By Vijay Sharma, Digvijay Vikas Suryawanshi, DJ Lalneiruol
| ijfmr.com
ABSTRACT Background: Unconsciousness is a critical and life-threatening presentation in the emergency department, associated with high morbidity and mortality. Non-traumatic unconsciousness represents a diagnostic and prognostic challenge due to diverse etiologies and absence of reliable history. Early assessment of severity and identification of underlying causes are essential for appropriate management and outcome prediction.
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Integrated morpho-physiological and biochemical responses of wheat genotypes to terminal heat stress and their role in determining grain yield

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By Vijay Sharma, Mukul Kumar, Pawan Prajapati, Mohd Ali, Harsh Jainth, Suman Bakshi, Himani Maheshwari
| Nature Verified
Abstract Terminal heat stress is a major constraint to wheat production under global climate change, necessitating the identification of key adaptive traits and tolerant genotypes. This study evaluated 13 bread wheat (Triticum aestivum L.) genotypes under optimal and heat-stress conditions, focusing on morphological, physiological, and biochemical traits at the grain-filling stage.
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