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Vijayakanth Pagadala on Muck Rack

Vijayakanth Pagadala

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Articles

Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: Paving the way to a diverse library for glycobiologists

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By Xing Zhang, Andrew Lim, Vijayakanth Pagadala, Hannah M. Jester
| Royal Society of Chemistry Verified
Heparan sulfate (HS) is a member of the glycosaminoglycans (GAG) family that plays essential roles in biological processes from animal sources. Heparin, a highly sulfated form of HS, is widely used as anticoagulant drug worldwide. The high diversity and complexity of HS and heparin represent a roadblock for structural characterization and biological activity studies.
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