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Villacorta-Martin C

As seen in: National Institutes of Health, Ash Publications
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Articles by Villacorta-Martin C

Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures

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By Villacorta-Martin C, Edwards CV, Lindstrom-Vautrin J, Golden CS
| ncbi.nlm.nih.gov
Background: In ATTR amyloidosis, transthyretin (TTR) protein is secreted from the liver and deposited as toxic aggregates at downstream target tissues. Despite recent advancements in treatments for ATTR amyloidosis, the mechanisms underlying misfolded TTR-mediated cellular damage remain elusive.
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Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme

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By Villacorta-Martin C, Alber AB, Marquez HA, Thapa BR
| ncbi.nlm.nih.gov
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De novo hematopoiesis from the fetal lung

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By Villacorta-Martin C, Lindstrom-Vautrin J
| Ash Publications
Hematopoietic stem cells (HSCs) originate from a rare subpopulation of arterial endothelial cells known as HECs. Making up just 1% to 3% of the total endothelial cell population in the aorta-gonad-mesonephros (AGM), HECs are commonly thought to be confined to a small window of gestation between embryonic days 8 to 11 (E8-11) in mice and E27-40 in humans.1,2 Within this time window, HECs can also be found in other hematopoietic organs and vessels, including the yolk sac, placenta, and...
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A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells

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By Kaserman JE, Villacorta-Martin C, Jean JC, Liberti DC
| National Institutes of Health
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