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Vilmante Kodyte on Muck Rack

Vilmante Kodyte

As seen in: Nature, BioRxiv
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Articles

Structural basis for transcription activation through cooperative recruitment of MntR - Nature Communications

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By Haoyuan Shi, Vilmante Kodyte, Amelie Andreas, Ankita Sachla, Ritu Shrestha, John D. Helmann, Arthur Glasfeld
| Nature Verified
Abstract Bacillus subtilis MntR is a dual regulatory protein that responds to heightened Mn2+ availability in the cell by both repressing the expression of uptake transporters and activating the expression of efflux proteins. Recent work indicates that, in its role as an activator, MntR binds several sites upstream of the genes encoding Mn2+ exporters, leading to a cooperative response to manganese.
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Structural basis for transcription activation through cooperative recruitment of MntR

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By Haoyuan Shi, Yu Fu, Vilmante Kodyte, Amelie Andreas
| BioRxiv
Abstract The manganese transport regulator (MntR) from B. subtilis is a dual regulatory protein that responds to heightened Mn2+ availability in the cell by both repressing the expression of uptake transporters and activating the expression of efflux proteins. Recent work indicates that, in its role as an activator, MntR binds several sites upstream of the genes encoding Mn2+ exporters, leading to a cooperative response to manganese.
Open in Who Shared Issue with article?
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