Vince J. Murphy

How Are Baan and Infor LN ERP Systems Like an Airplane? That sounds like the start of a bad joke, right? (I should know because I can tell some bad jokes — just ask my kids.) But both airplanes and enterprise resource planning (ERP) systems are highly complex and highly engineered products. An airplane consists of thousands upon thousands of parts that must be built and put together within narrow tolerances for the airplane to fly.

Arizona’s MAGA Republicans are tarnishing American democracy and pose an active threat to their state’s voters and future elections. Arizona Republican’s lineup of legislative candidates has helped conduct a costly, sham election review after the 2020 election – not to mention spread dangerous conspiracy theories, called for hundreds of thousands of Arizonans’ voices to be silenced, or even traveled to DC for the rally-turned-attack.

Abstract DNA inter-strand crosslinks (ICLs) threaten genomic stability by creating a physical barrier to DNA replication and transcription. ICLs can be caused by endogenous reactive metabolites or from chemotherapeutics. ICL repair in humans depends heavily on the Fanconi Anaemia (FA) pathway. A key signalling step of the FA pathway is the mono-ubiquitination of Fanconi Anaemia Complementation Group D2 (FANCD2), which is achieved by the multi-subunit E3 ligase complex.