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Vincent Louis Pecoraro on Muck Rack

Vincent Louis Pecoraro

As seen in: Color Research & Application, Wiley Online Library
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Articles

Catalysis and Electron Transfer in De Novo Designed Helical Scaffolds - Pinter - - Angewandte Chemie International Edition - Wiley Online Library

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By Karl Koebke, Vincent Louis Pecoraro
| Arthritis & Rheumatology Verified
Review Catalysis and Electron Transfer in De Novo Designed Helical Scaffolds Vincent Louis Pecoraro Corresponding Author E-mail address: vlpec@umich.edu University of Michigan, Department of Chemistry, 930 n. University, 48109-1055 Ann Arbor, UNITED STATES Search for more papers by this author PDF PDF Share Abstract The relationship between protein structure and function is one of the greatest puzzles within biochemistry.
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Modifying the Sterics In the Second Coordination Sphere Of Designed Peptides Leads to Enhancement of Nitrite Reductase Activity

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By Karl Koebke, Fangting Yu, Elvin Salerno, Casey Van Stappen, Alison Tebo, James Penner-Hahn, Vincent Louis Pecoraro
| Color Research & Application Verified
Protein design is a useful strategy to interrogate the protein structure-function relationship. We demonstrate using a highly modular 3-stranded Coiled Coil (TRI-peptide system) that a functional type 2 copper center exhibiting copper nitrite reductase (NiR) activity exhibits the highest homogeneous catalytic efficiency under aqueous conditions for the reduction of nitrite to NO and water.
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