Viral Chikani

References 1  Queensland Health. The health of Queenslanders, 2020. Report of the Chief Health Officer of Queensland. Brisbane: Queensland Government; 2020. 2  Queensland Government Statistician’s Office. Aboriginal and Torres Strait Island people in Queensland, Census 2016. In: Queensland Treasury, editor. Queensland Government; 2016. 3  Australian Bureau of Statistics. National Aboriginal and Torres Strait Islander Health Survey 2018-19. Contract No.: 4715.0. Australian Bureau of Statistics; 2019.

Skeletal muscle is a target tissue of GH. Based on its anabolic properties, it is widely accepted that GH enhances muscle performance in sports and muscle function in the elderly. This paper critically reviews information on the effects of GH on muscle function covering structure, protein metabolism, the role of IGF1 mediation, bioenergetics and performance drawn from molecular, cellular and physiological studies on animals and humans.

Anaerobic and aerobic energy systems. AA, amino acid; FA, fatty acid; TCA, tricarboxylic acid cycle; O2, oxygen. Schematic diagram of changes in the expression of key genes in the skeletal muscle governing the oxidative metabolism of FAs and glucose after GH therapy (data from Sjogren et al. (2007)). Metabolic genes that were downregulated by GH in the skeletal muscle are boxed in green with the abbreviated names expanded below. FA, fatty acid; TCA, tricarboxylic acid cycle.