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Vishwesh Patil on Muck Rack

Vishwesh Patil

As seen in: Frontiers
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Articles

C-1101 multi-protein platelet and plasma-derived therapeutic to treat chronic lumbosacral radiculopathy

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By Peter Wilhelm Linde, Lyndah Chow, Teresa Wright, Steven Dow, Lynn Pezzanite, Renata Impastato, Vishwesh Patil, Jennifer Schmitke
| Frontiers
Abstract Introduction: Intervertebral disc disease (IVDD) leads to chronic lumbosacral radiculopathy (LSR) with nerve root compression resulting in numbness and low back pain. The aim was to evaluate therapeutic and immunomodulatory potential of multi-protein platelet and plasma-derived biologic (C-1101) to alter inflammatory mediators and gene expression in IVDD. Methods: In aim 1, intervertebral discs and dorsal root ganglia (DRG) were harvested from female ovine lumbar spines (n = 6).
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