Volkmar Thom on Muck Rack

Volkmar Thom

Bielefeld
As seen in: abgefahren-leben.de, AIChE Journal, Wiley Online Library, BioPharm International
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Articles

A high‐throughput approach to developing and optimizing mixed‐mode membrane chromatography for protein purification

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By William S. McKechnie, Volkmar Thom, Lukas Kupracz, Jennifer Pollard
| AIChE Journal Verified
Abstract Membrane chromatography has been established as a viable alternative to packed-bed column chromatography for the purification of therapeutic proteins. Purification via membrane chromatography offers key advantages, including higher productivity and reduced buffer usage. Unlike column chromatography purification, the utilization of high-throughput screening in order to reduce development times and material requirements has been a challenge for membrane chromatography.
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Streamlined process development procedure incorporating the selection of various stationary phase types established in a mAb aggregate reduction study with different mixed mode ligands

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By Dominik Stein, Volkmar Thom, Jürgen Hubbuch
| AIChE Journal Verified
RESEARCH ARTICLE Dominik Stein, Corresponding Author Dominik Stein dominik.stein@sartorius.com orcid.org/0000-0001-6712-5762 Sartorius Stedim Biotech GmbH, August-Spindler-Str. 11, D-37079, Goettingen, Germany Dept.
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HTS Setup of a Scale‐down Device for Membrane Chromatography ‐ Aggregate Removal of Monoclonal Antibodies

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By Dominik Stein, Volkmar Thom, Jürgen Hubbuch
| AIChE Journal Verified
RESEARCH ARTICLE Dominik Stein Corresponding Author E-mail address: Dominik.Stein@sartorius.com https://orcid.org/0000-0001-6712-5762 Sartorius Stedim Biotech GmbH, August‐Spindler‐Str. 11, D‐37079, Goettingen Dept.
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