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Cover Image - Tordesillas - 2017 - Clinical & Experimental Allergy - Wiley Online Library
AbstractThe cover image, by P. Brinkman et al., is based on the Original Article Exhaled breath profi les in the monitoring of loss of control and clinical recovery in asthma, DOI: 10.1111/cea.12962.
Histamine Receptor 2 Modifies iNKT Cell Activity within the Inflamed Lung
Histamine is a key immunoregulatory mediator and can dampen proinflammatory responses via activation of histamine receptor 2 (H 2 R). The aim of this study was to determine the role of H 2 R in modulating lung inflammatory responses. H 2 R was blocked using famotidine or activated using dimaprit in both the ovalbumin (OVA) and house dust mite extract (HDM) murine models of respiratory inflammation.
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