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W. Dean Pontius on Muck Rack

W. Dean Pontius

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Articles

Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis - Nature Communications

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By Zachary J. Faber, Craig D. Peacock, Diana H. Chin, W. Dean Pontius
| Nature Verified
Abstract The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately grow within a secondary organ. Despite metastasis being a dynamic, multistep process, most omics studies to date have focused on comparing primary tumors to the metastatic deposits that define end-stage disease.
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