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Keywords Ceftobiprole Critical illness Infectious disease Microbiology Pharmacokinetics 1. BACKGROUND Ceftobiprole (CBP) is a recently developed β-lactam antibiotic of particular interest. It is a 5th-generation cephalosporin with a broad spectrum [1], [2], [3], acting against both Gram-negative and Gram-positive bacteria, particularly methicillin-resistant Staphylococcus aureus (MRSA)[4], [5].
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