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Waddah A. Alrefai on Muck Rack

Waddah A. Alrefai

As seen in: Nature, Gastrointestinal Endoscopy
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235 THE SEROTONIN TRANSPORTER REGULATES COLONIC OXIDATIVE STRESS THROUGH THE GUT MICROBIOTA

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By Aisha Qazi, Saleha Hashim, Ramsha Akram, Pradeep K. Dudeja, Seema Saksena, Waddah A. Alrefai, Ravinder K. Gill
| Gastrointestinal Endoscopy Verified
Also available on ScienceDirect
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Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR

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By Christopher Manzella, Megha Singhal, Waddah A. Alrefai, Seema Saksena
| Nature Verified
The classic physiological functions of 5-HT in the GI tract mainly relate to initiation of peristalsis, visceral sensation, and controlling movement of fluid and electrolytes, which are mediated by activation of specific 5-HTR subtypes. Studies over the past decade have revealed a new role for 5-HT and SERT in the pathophysiology of intestinal inflammatory disorders, but the molecular mechanisms that contribute to this association are poorly understood25,26,27,38.
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