Wagner Vasques Dominguez

4. Discussion In recent years, research has been carried out with the objective of identifying serum and urinary biomarkers, the determination of which is less invasive, that could replace renal biopsy for the differential diagnosis of glomerulopathies. In addition to facilitating the diagnosis, such biomarkers are also expected to provide information on the type of response to immunosuppressive therapy, as has been demonstrated in membranous nephropathy.

Abstract Background/objective Loss of renal function may induce secondary hyperparathyroidism (s-HPT), which triggers several complications leading to an extreme decline in quality of life and increased mortality in affected patients. We evaluated whether parathyroidectomy (PTx), as surgical treatment for s-HPT, modifies body composition, and hormones involved in the protein-energy metabolism of affected patients.