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Wanfu Xie on Muck Rack

Wanfu Xie

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Articles

F13A1 enhances temozolomide resistance in glioblastoma via activation of the NF-κB signalling pathway

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By Beichen Zhang, Haoyu Zhou, Jia Wang, Xiao Yu, Zhounan Wang, Bin Liu, Wei Wu, Xiaoye Guo, Xiaobin Bai, Wanfu Xie
| Nature Verified
Abstract Acquired resistance to temozolomide (TMZ) is a principal driver of therapeutic failure and tumour recurrence in glioblastoma (GBM). This study sought to elucidate the molecular underpinnings of this resistance, aiming to identify viable prognostic markers and therapeutic targets to refine personalized treatment strategies. We integrated gene expression and clinical data from the GEO, TCGA, and CGGA databases.
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