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Waseem Ashraf

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Articles

Evaluation of gaps in life cycle sustainability assessments of 3D concrete printing: A systematic literature review and recommendations

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By Waseem Ashraf, Resource-Efficient Construction, Mohammed Alokshiya
| tu-dresden.de
The construction industry significantly contributes to global carbon emissions, resource depletion, and environmental degradation, necessitating sustainable innovations. 3D concrete printing (3DCP) has emerged as a transformative technology offering design flexibility, reduced material waste, and improved efficiency. However, sustainability assessments of 3DCP remain fragmented.
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Rufinamide Mitigates Seizures and Behavioural Deficits via BDNF/TrkB Modulation and Oxidative Stress Reduction in Pentylenetetrazole‐Kindled Mice

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By Saima Muhammad Abbas, Abida Parveen, Waseem Ashraf, Faleh Alqahtani
| Wiley Online Library Verified
Background Rufinamide (RUF) is a 3rd generation antiseizure medication (ASM) with a triazole ring that blocks voltage-gated sodium channels (VGSCs) and is most commonly used to treat Lennox–Gastaut syndrome. Thus, the present study examined the effect of RUF on EEG activity, behavioural testing, oxidative stress, and mRNA expression in PTZ-kindled mice.
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Polypharmacy with tiagabine, levetiracetam, and perampanel in status epilepticus: Insights from EEG, biochemical, and histopathological studies in rats

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By Faleh Alqahtani, Abida Parveen, Waseem Ashraf
| Wiley Online Library Verified
Treatment with low-dose tiagabine (TGB), levetiracetam (LEV), and perampanel (PER) as monotherapy proved insufficient to provide behavioral and ictal attenuation in experimental model of status epilepticus. Combining the low doses of TGB, LEV, and PER prominently caused seizure attenuation and reversal of SE-associated electrographic changes. The drug combination markedly protected the rats from SE-induced oxidative stress and morphological alterations in CA1 and DG regions of hippocampus.
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