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Wei-Yin Wu

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Articles

METTL14-dependent N 6 -methyladenosine modification of FGF16 participates in IGFBP5 deficiency-enhanced angiogenesis

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By YU HU, Shan-Shan Zhao, Yutian Wang, Le Fu Zhang, Yan Wang, Yi-Xiang Hong, Hui-Zhu Huang, Wei-Yin Wu
| Nature Verified
Abstract N6-methyladenosine (m6A) RNA modification plays critical roles in physiological and pathological processes. Our prior study demonstrated that IGFBP5 expression is upregulated in the ischemic limb, whereas endothelial-specific IGFBP5 knockout (Igfbp5EKO) protects against hind limb ischemia by enhancing angiogenesis.
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