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Articles by Weiming Chen
A Comprehensive Digital Pathology Dataset for Liver Cancer Research
Abstract Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment selection and patient survival, and pathological examination remains the gold standard for liver cancer diagnosis. Identifying diverse tissue components and pathological subtypes on histopathology slides is crucial for estimating postoperative recurrence risk and overall prognosis.
ODC1 inhibition and neuroblastoma: A drug-target Mendelian randomization, eQTL colocalization and drug sensitivity study
DATA AVAILABILITY STATEMENT Data are provided within the manuscript or files. Supporting Information Filename Description BCP70786-sup-0001-SupplementaryFigure1.tifTIFF image, 242.9 KB Figure S1 Leave-one-out of SNPs associated with ODC and their risk of NB. Each black point represents result of the IVW MR method applied to estimate the causal effect of ODC on NB excluding particular SNP.
Computer Science > Computer Vision and Pattern Recognition
Multiple instance learning (MIL) is widely used for weakly supervised whole slide image (WSI) analysis. However, under long-tailed distributions, MIL-based WSI analysis faces a nested dual long-tail: an inter-slide class long tail and an intra-slide long tail of instance-level discriminative evidence.
Preoperative geriatric nutritional risk index (GNRI) as a predictor of intraoperative hypothermia in esophageal cancer surgery
Keywords GNRI Esophageal cancer Intraoperative hypothermia Predictive marker 1 Introduction Esophageal cancer (EC) remains one of the most significant malignancies threatening human health, with its incidence rate increasing annually. Projections suggest that the global incidence of EC may rise by 58% by 2040 compared to 20201,2. Currently, the primary therapeutic approach for EC involves multimodal therapy centered on surgical intervention.
Understanding the immune microenvironment of ovarian cancer
Abstract Ovarian cancer remains the most lethal gynecological malignancy, yet immune checkpoint inhibitors (ICIs) demonstrate limited clinical efficacy due to profound CD8+- T cell exhaustion within a highly heterogeneous tumor immune microenvironment (TME). Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of this complex ecosystem by resolving rare immune subsets, reconstructing lineage trajectories, and mapping dynamic intercellular signaling networks.
A General Selenium-Anchoring Strategy for the Synthesis of Subnanometer Metal Cluster Catalysts
Abstract Click to copy section linkSection link copied! Supported subnanometer metal cluster catalysts possess catalytic sites with multiple metal atoms as in nanoparticles (NPs) and maintain high atomic utilization efficiency as in single-atom catalysts (SACs), making them an emerging type of catalyst to bridge SACs and NPs. However, their controllable synthesis remains a significant challenge.
[2510.27335] Understanding the Implicit User Intention via Reasoning with Large Language Model for Image Editing
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Establishment and validation of a nomogram to predict thirty-day unplanned reoperations of primary anastomosis in neonates with intestinal atresias
ORIGINAL RESEARCH article Volume 13 - 2025 | https://doi.org/10.3389/fped.2025.1660827 Introduction Intestinal atresia (IA) as one of the most common causes of neonatal bowel obstruction requires operative repair in the early neonatal period (1). Primary anastomosis has emerged as the preferred surgical approach due to its advantages of shorter hospital stays and avoidance of stoma-related complications (2–4). The unplanned reoperations rates in IA varied considerably from 11%–25% (5–7).
Weight-Adjusted Waist Index
Hongjin Wang,1,* Weiming Chen,2,* Feilong Guo,2,* Zengkai Xu,1 Xin Luo,1 Jiahuang Wu,1 Yong Zhu,2 Zhisheng Wang1 1Department of Cardiovascular Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, People’s Republic of China; 2Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, People’s Republic of China *These authors contributed equally to this work Correspondence: Zhisheng Wang, Email [email protected] Yong Zhu, Email...
Thermomigration Microstructure and Properties of Ni Nanoparticle-Reinforced Sn58Bi Composite Solder/Cu Solder Joint
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Boron-Mediated Selective C–H Hydroxylation of 1-Phenyl-1H-Pyrazoles
The Journal of Organic Chemistry Cite this: J. Org. Chem. 2024, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
Naples Prognostic Score as a novel prognostic prediction tool for rese
Weiming Chen,1– 3,* Guobing Xu,1– 3,* Xin Yan,4,* Shuo Wang,1– 3 Qichang Xie,1– 3 Qing Liu,5 Bin Zheng,1– 3 Chun Chen,1– 3 Yong Zhu,1– 3 Zhang Yang1– 3 1Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, People’s Republic of China; 2Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fuzhou, Fujian, People’s Republic of China; 3Clinical Research Center for Thoracic Tumors of Fujian Province, Fuzhou, Fujian, People’s...
Redox‐Neutral Nickel‐Catalyzed Selective Hydroalkynylation of Internal Alkyne and Its Application in Anticancer Agent Discovery†
Supporting Information Filename Description cjoc202400655-sup-0001-supinfo.pdfPDF document, 9.8 MB Appendix S1: Supporting Information References 1 ; ; ; ; ; Copper-catalyzed functionalization of enynes. Chem. Sci. 2020, 11, 11380–11393. 2 ; ; ; Regiodivergent sulfonylarylation of 1, 3-enynes via nickel/photoredox dual catalysis. Chem. Sci. 2021, 12, 13564–13571. 3 ; ; ; ; ; ; trans-Hydroalkynylation of internal 1,3-enynes enabled by cooperative catalysis. J. Am. Chem. Soc. 2023, 145, 5624–5630.
Pretreatment system inflammation response index (SIRI) is a valuable m
Back to Journals » International Journal of General Medicine » Volume 17 Original Research Oncology Authors Zhang Y, Wu J, Chen W, Liang X Received 12 May 2024 Accepted for publication 20 September 2024 Published 25 September 2024 Volume 2024:17 Pages 4359—4368 DOI https://doi.org/10.2147/IJGM.S478000 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Kenneth Adler Yunuo Zhang,1 Jingna Wu,1 Weiming Chen,2...
Climate Change Reduces the Effectiveness of Myanmar’s Protected Area Network
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 9 April 2024 / Approved: 10 April 2024 / Online: 10 April 2024 (09:44:57 CEST) Chen, W.; Wu, M. Climate Change Reduces the Effectiveness of Myanmar’s Protected Area Network. Preprints 2024, 2024040704. https://doi.org/10.20944/preprints202404.0704.v1 Chen, W.; Wu, M. Climate Change Reduces the Effectiveness of Myanmar’s Protected Area Network. Preprints 2024, 2024040704.
Chemoselective C-H Hydroxylation and Borylation of N-Phenylbenzamides using BBr3
CCDC 2339827 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, U.K.; fax: +44 1223 336033. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.
Chemoselective C-H Hydroxylation and Borylation of N-Phenylbenzamides using BBr3
CCDC 2339827 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, U.K.; fax: +44 1223 336033. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.
Association between haemoglobin-to-red blood cell distribution width ratio at admission and all-cause mortality in adult patients with sepsis in an intensive care unit: a secondary analysis of the MIMIC-IV database
Discussion The present study explored the potential relationship between HRR at ICU admission and the risk of all-cause mortality among patients with sepsis, indicating that individuals with lower HRR levels face higher mortality risks at 1-year and 30-day intervals. These findings are significant, suggesting HRR’s utility as a valuable marker for overall survival in patients with sepsis.
Metal-Sulfur Interfaces as the Primary Active Sites for Catalytic Hydrogenationsf
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Endogenously Gated DNA Walking Machine for Prescreened MicroRNA Detection in Extracellular Vesicles
Download Hi-Res ImageDownload to MS-PowerPointCite This:Anal. Chem. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Clinical features and outcomes of children’s interstitial lung disease accompanied with connective tissue disease: A prospective cohort study
Medical complexity of childhood interstitial lung disease (chILD) with connective tissue disease (CTD) poses a considerable challenge to pediatricians. Clinical characteristics, laboratory findings, pulmonary function tests (PFTs), treatments and outcomes obtained for patients with CTD-chILD were analyzed in a prospective study. Patients’ median age at diagnosis was 7 years old.
Effect of Ultrasonic Treatment on Structure, Antibacterial Activity of Sugarcane Leaf Polysaccharides
This study investigated the impact of ultrasonic extraction (UE) on the structure and in vitro antibacterial activity of polysaccharides from sugarcane leaves (SLW). Native sugarcane leaf polysaccharides were treated with ultrasound (480 W) for 3 h to yield sugarcane leaf polysaccharides (SLU). Compared to SLW (33.59 kDa), the molecular weight of SLU (13.08 kDa) was significantly decreased, while the monosaccharide composition of SLU was unchanged.
Molecular Characteristics and Formation Mechanisms of Unknown Ozonation Byproducts during the Treatment of Flocculated Nanofiltration Leachate Concentrates Using O3 and UV/O3 Processes
Both ozone (O3) and UV/O3 treatment processes can effectively remove organic matter in the flocculated membrane filtration concentrate from landfill leachate, but the ozonation byproducts (OBPs) generated in the processes remain unknown.
Associations of specific dietary unsaturated fatty acids with risk of overweight/obesity: population-based cohort study
Introduction Overweight and obesity are a great burden to the world, with the events of overweight and obesity tripling to 1.6 billion in 2016 compared to 1975s (1). Notably, overweight and obesity are vital risk factors for noncommunicable diseases including cardiovascular disease and cancer, which are leading causes of death (2, 3). China is also threatened by the epidemic of overweight and obesity.
Sugarcane molasses essential oils: Mesoporous silica nanoparticles as carriers to improve its slow-release activity and the study on its anti-inflammatory activity in vivo
Sugarcane molasses essential oils: Mesoporous silica nanoparticles as carriers to improve its slow-release activity and the study on its anti-inflammatory activity in vivo Fengyu Jiang, Weiming Chen, Kai Zhang, Mengmiao Mo, Zhendong Ding, Yong-guang Bi and Fansheng Kong Abstract In this manuscript, sugarcane molasses essential oils (SMEO) were extracted using microwave-assisted hydrodistillation (MAHD); the components of SMEO were identified and analyzed by gas chromatography-mass...
Bolt Positioning Detection Based on Improved YOLOv5 for Bridge Structural Health Monitoring
Abstract : To improve the stability of the bridge structure, we detect bolts in the bridge which cause the symmetry failure of the bridge center. For data acquisition, bolts are small-scale objects under complex background in images, and their feature expression ability is limited. Due to those questions, we propose a new bolt positioning detection based on improved YOLOv5 for bridge structural health monitoring. This paper makes three major contributions.
IIIandMe: An Algorithm for Chromosome-scale Haplotype Determination Using Genome-wide Variants of Three Haploid Reproductive Cells
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The Use of Membranes (ST-100, oXiris, and M60) for Continuous Renal Replacement Therapy in a Child with Sepsis
Sepsis is a critical condition affecting patients worldwide. Systemic inflammatory response syndrome in sepsis contributes to organ dysfunction and mortality. The oXiris is a recently developed continuous renal replacement therapy (CRRT) hemofilter indicated for the adsorption of cytokines from the bloodstream. In our study, in a septic child, CRRT with three filters, including the oXiris hemofilter, resulted in a downregulation of inflammatory biomarkers and a reduction of vasopressors.
Pharmacokinetics of meropenem in children with sepsis undergoing extracorporeal life support: A prospective observational study
Abbreviations AKI acute kidney injury ALT alanine aminotransferase AST aspartate aminotransferase AUC area under the curve AUC0‐∞ area under the plasma concentration‐time curve from time zero to infinity AUCtau area under the plasma concentration‐time curve CL clearance CLSS clearance at steady‐state CRP C‐reactive protein CRRT continuous renal replacement therapy CVVHDF continuous veno‐venous haemodialysis eCLCR estimated creatinine clearance ECLS extracorporeal life support ECMO...
General synthesis of single atom electrocatalysts via a facile condensation-carbonization process
General synthesis of single atom electrocatalysts via a facile condensation–carbonization process† Weiming Chen,a Xuanli Luo,c Thomas J. A.
Gram-scale synthesis of monodisperse sulfonated polystyrene nanospheres for rapid and efficient sequestration of heavy metal ions
B. GONG, Y. Peng, Z. Pan, W. Chen, Y. Shen, K. Xiao and L. Zhang, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC07397F If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
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