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Fully automated system predicts osteoporotic vertebral fracture across institutions using lumbar MRI paraspinal muscle signatures
Abstract Paraspinal muscle (PM) degeneration is a crucial yet frequently overlooked risk factor for osteoporotic vertebral fractures (OVF). We developed PM Segmentation and Classification of OVF (PMSAC-OVF), a fully automated, multi-institutional system that segments lumbar PMs on MRI, extracts federated learning (FL) and radiomics features, and integrates them with clinical variables for OVF prediction.
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