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Weiying Ye

As seen in: Nature
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Articles

Author Correction: Kalium channelrhodopsins effectively inhibit neurons - Nature Communications

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By Stanislav Ott, Sangyu Xu, Nicole Lee, Ivan Hong, Jonathan Anns, Danesha Devini Suresh, Zhiyi Zhang, Xianyuan Zhang, Raihanah Harion, Weiying Ye, Vaishnavi Chandramouli, Suresh Jesuthasan, Yasunori Saheki
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-47203-w, published online 24 April 2024 In this article, one affiliation for Adam Claridge-Chang was incorrectly given as Department of Pharmacy, National University of Singapore, Singapore, Singapore but should have been Department of Physiology, National University of Singapore, Singapore, Singapore. The original article has been corrected.
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Exploring bat-inspired cyclic tryptophan diketopiperazines as ABCB1 Inhibitors - Communications Chemistry

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By Yoko Itahana, Alexander Krah, Weiying Ye, Lin-Fa Wang, Roderick W. Bates, Yasuhisa Kimura, Peter J. Bond, Dona Mariya Vincent, Sabhashina Radha Krishnan
| Nature Verified
Abstract Chemotherapy-induced drug resistance remains a major cause of cancer recurrence and patient mortality. ATP binding cassette subfamily B member 1 (ABCB1) transporter overexpression in tumors contributes to resistance, yet current ABCB1 inhibitors have been unsuccessful in clinical trials. To address this challenge, we propose a new strategy using tryptophan as a lead molecule for developing ABCB1 inhibitors.
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Kalium channelrhodopsins effectively inhibit neurons - Nature Communications

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By Stanislav Ott, Sangyu Xu, Nicole Lee, Ivan Hong, Jonathan Anns, Zhiyi Zhang, Suresh Jesuthasan, Yasunori Saheki, Danesha Devini Suresh, Xianyuan Zhang, Raihanah Harion, Weiying Ye, Vaishnavi Chandramouli
| Nature Verified
Abstract The analysis of neural circuits has been revolutionized by optogenetic methods. Light-gated chloride-conducting anion channelrhodopsins (ACRs)—recently emerged as powerful neuron inhibitors. For cells or sub-neuronal compartments with high intracellular chloride concentrations, however, a chloride conductance can have instead an activating effect.
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