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Rhodium(III)‐Nitroxyl Radical Complex Triggers Dual‐Pronged Disulfidptosis‐Apoptosis in Hepatocellular Carcinoma via Metabolic Sabotage and Redox Catalysis
Conflict of Interests The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie70544-sup-0001-SuppMat.docx10.6 MB Supporting Information anie70544-sup-0002-Data.zip14.9 KB Supporting Information References 1, , , , , , , CA-Cancer J. Clin. 2024, 74, 229–263.
Copper(II) complex enhanced chemodynamic therapy through GSH depletion and autophagy flow blockade
Copper(ii) complex enhanced chemodynamic therapy through GSH depletion and autophagy flow blockade† Wen-Ying Shen,‡ab Chun-Peng Jia,‡a Li-Yi Liao,a Liu-Lin Chen,a Cheng-Cheng Yuan,a Yun-Qiong Gu,a Yang-Han Liu,a Hong Liang*a and Zhen-Feng Chen *a Abstract Three copper(II) complexes C1–C3 were synthesized and fully characterized as chemodynamic therapy (CDT) anticancer agents. C1–C3 showed greater cytotoxicity than their ligands toward SK-OV-3 and T24 cells.
Ru(III) complexes with pyrazolopyrimidines as anticancer agents: bioactivities and the underlying mechanisms
Ru(iii) complexes with pyrazolopyrimidines as anticancer agents: bioactivities and the underlying mechanisms† Yun-Qiong Gu,‡ab Wen-Ying Shen,‡a Qi-Yuan Yang,a Zhen-Feng Chen *a and Hong Liang*a Author affiliations * Corresponding authors a State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Centre for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, P. R.
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