Wenjuan Ying

Introduction Plastic surgery–related diseases encompass a broad spectrum of conditions—including cancers, congenital anomalies, soft tissue infections, ulcers, and trauma—that frequently require surgical intervention, wound reconstruction, or aesthetic rehabilitation (1, 2). These conditions not only cause significant morbidity and mortality but also impose considerable social and economic burdens through disfigurement, disability, and long-term care needs (3, 4).

ORIGINAL RESEARCH article Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1633242 This article is part of the Research TopicEquity in Cancer Prevention and Early DetectionView all 7 articles Introduction Colorectal cancer (CRC), originating in the colon or rectum, remains one of the leading causes of cancer-related morbidity and mortality worldwide (1, 2).

Introduction Major depressive disorder (MDD) is a leading cause of disability worldwide, associated with substantial morbidity, mortality, and societal costs, and affects up to 20% of the population (1). Symptoms of MDD include depressed mood, anhedonia (loss of interest or pleasure), changes in appetite, fatigue, and impaired concentration (2).