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Wenyin Su on Muck Rack

Wenyin Su

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Articles

Deconvolution of the On-Target Activity of Plasmepsin V Peptidomimetics in Plasmodium falciparum Parasites

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By William Nguyen, Ghizal Siddiqui, Jerzy M. Dziekan, Wenyin Su
| ACS Publications
There is an urgent need to develop new strategies and agents to treat malaria because of the emergence of resistance against antimalarial therapies in clinical use. (1,2) This is particularly significant given that malaria continues to pose a substantial global health burden, with an estimated 263 million cases and 597,000 deaths reported in 2023. (2) Plasmodium falciparum expresses 10 cathepsin-D-like aspartyl proteases termed plasmepsins (PM).
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