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Assessment of paper tip angular position, carryover, matrix effects and dried blood spot storage effect on paper spray mass spectrometry
Assessment of paper tip angular position, carryover, matrix effects and dried blood spot storage effect on paper spray mass spectrometry† John Takyi-Williams, ‡*a Wenying Jian,b Yang Wang,b Kai Tang,c Haiqing Gong§d and Chuan-Fa Liu *a Author affiliations * Corresponding authors a School of Biological Sciences, Nanyang Technological University, Singapore E-mail: john006@e.ntu.edu.sg, CFLIU@ntu.edu.sg Tel: +65 27734473828 b Janssen Research & Development LLC, 1400 McKean Road, Spring House,...
Assessment of paper tip angular position, carryover, matrix effects and dried blood spot storage effect on paper spray mass spectrometry
Assessment of paper tip angular position, carryover, matrix effects and dried blood spot storage effect on paper spray mass spectrometry Paper Spray (PS) ionization has been demonstrated extensively for rapid quantitation of pharmaceuticals in dried matrix spots. In this study, experimental and validation parameters of paper spray mass spectrometry were explored.
LC-MS bioanalysis of intact proteins and peptides
REVIEW Wenying Jian Corresponding Author E-mail address: wjian@its.jnj.com Drug Metabolism and Pharmacokinetics (DMPK), Janssen Pharmaceutical Companies of Johnson and Johnson, Spring House, PA Correspondence Wenying Jian, Drug Metabolism and Pharmacokinetics (DMPK), Janssen Pharmaceutical Companies of Johnson and Johnson, 1400 McKean Road, Spring House, PA 19477.
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