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Granulocyte transfusions in severe aplastic anemia

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By Rajput RV, Shalhoub RN, West-Mitchell K, Cha NR
| aamds.org
Patients with severe (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response.
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