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Systematic Literature Review of Outcomes Associated With Adherence to Haemophilia Drug Therapy
1 Introduction The treatment landscape for persons with haemophilia A (HA) and B (HB) (PwH) has expanded, and current options include factor replacement therapies, nonfactor therapies and gene therapies [1, 2] offering improved life expectancy for PwH similar to that of the general population [3]. Factor replacement therapies consist of intravenously administered Factor VIII (FVIII) or IX (FIX) proteins and can be used as prophylaxis or as on-demand treatment [3, 4].
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