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Articles by William Matlock
Global genomic epidemiology of bla GES-5 carbapenemase-associated integrons
Article metrics loading... /content/journal/mgen/10.1099/mgen.0.001312 Download as PowerPoint /deliver/fulltext/mgen/10/12/mgen001312.html?itemId=/content/journal/mgen/10.1099/mgen.0.001312&mimeType=html&fmt=ahah References Baquero F, Martínez JL, F Lanza V, Rodríguez-Beltrán J, Galán JC et al. Evolutionary pathways and trajectories in antibiotic resistance. Clin Microbiol Rev 2021; 34:e0005019 [View Article] [PubMed] [Google Scholar] Sheppard AE, Stoesser N, Wilson DJ, Sebra R, Kasarskis A et al.
Towards quantifying plasmid similarity
Article metrics loading... /content/journal/mgen/10.1099/mgen.0.001290 Download as PowerPoint /deliver/fulltext/mgen/10/9/mgen001290.html?itemId=/content/journal/mgen/10.1099/mgen.0.001290&mimeType=html&fmt=ahah References Coluzzi C, Garcillán-Barcia MP, de la Cruz F, Rocha EPC. Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids. Mol Biol Evol 2022; 39:msac115 [View Article] [PubMed] [Google Scholar] Castañeda-Barba S, Top EM, Stalder T.
E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1
Abstract Co-amoxiclav resistance in E. coli is a clinically important phenotype associated with increased mortality. The class A beta-lactamase blaTEM-1 is often carried by co-amoxiclav-resistant pathogens, but exhibits high phenotypic heterogeneity, making genotype-phenotype predictions challenging. We present a curated dataset of n=377 E. coli isolates representing all 8 known phylogroups, where the only acquired beta-lactamase is blaTEM-1.
Author Correction: The plasmidome associated with Gram-negative bloodstream infections: a large-scale observational study using complete plasmid assemblies | Nature Communications
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-45761-7, published online 22 February 2024 In this article the author name William Matlock was incorrectly written as Willam Matlock. The original article has been corrected.
Global genomic epidemiology of blaGES-5 carbapenemase-associated integrons
Abstract Antimicrobial resistance (AMR) gene cassettes comprise an AMR gene flanked by short recombination sites (attI x attC or attC x attC). Integrons are genetic elements able to capture, excise, and shuffle these cassettes, providing 'adaptation on demand', and can be found on both chromosomes and plasmids. Understanding the patterns of integron diversity may help to understand the epidemiology of AMR genes.
Opposing chemosensory functions of closely related gustatory receptors
eLife assessment This valuable study focuses on the role of the Gr28 family of insect chemoreceptors. Using the Drosophila larva, the authors show that taste neurons expressing different members of this family of bitter taste receptors trigger opposite behavior – attraction and repulsion. They establish the minimal bitter taste receptor subunit composition needed in these neurons to mediate the repulsion of bitter tastants.
Flanker: a tool for comparative genomics of gene flanking regions
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