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Wilna Liebenberg on Muck Rack

Wilna Liebenberg

As seen in: MDPI
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Articles

Formulation and Ex Vivo Evaluation of Ivermectin Within Different Nano-Drug Delivery Vehicles for Transdermal Drug Delivery

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By Wilna Liebenberg, Eunice Maureen Steenekamp, Minja Gerber, Eunice Maureen
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Investigation and Evaluation of the Transdermal Delivery of Ibuprofen in Various Characterized Nano-Drug Delivery Systems

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By Admire Dube, Jeanri Myburgh, Wilna Liebenberg, Clarissa Willers
| MDPI
3. Results and Discussion 3.1. Examination of Physicochemical Properties of Ibuprofen 3.1.1. Solubility of Ibuprofen in PBS and N-Octanol An API is regarded as suitable for transdermal delivery if its aqueous solubility is greater than 1 mg/mL []. Laboratory testing calculated the aqueous solubility of ibuprofen as 0.651 mg/mL; therefore, API diffusion through the skin might be hindered since low aqueous solubility is not ideal for transdermal delivery.
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