Wirath Ben Ncir on Muck Rack

Wirath Ben Ncir

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Articles

First LDLRAP1 and Recurrent LDLR Mutations in Tunisian Families With Familial Hypercholesterolemia

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By Afif Ben-Mahmoud, Fatma Abdelhedi, Wirath Ben Ncir, Hamdi Frikha
| Wiley Online Library Verified
1 Introduction Familial hypercholesterolemia (FH) is an inherited disorder characterised by elevated serum low-density lipoprotein cholesterol (LDL-C), leading to premature atherosclerosis and cardiovascular disease. Excess LDL-C leads to cholesterol deposition in peripheral tissues (xanthomas) and accelerates atherosclerosis, promoting early-onset coronary heart disease [1].
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