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Wolfgang Pfeifer on Muck Rack

Wolfgang Pfeifer

Saarbrücken
As seen in: Nature, Science Magazine, BioRxiv
Covers:  bionik, bionic, apps for ipad, social media management, engineering, apps for iphone, social media, soziale medien, konstruktion, medienkompetenz, produktentwicklung, neue medien, soziale netzwerke, reinraumtechnik, lightweight design
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Articles

Piggybacking functionalized DNA nanostructures into live-cell nuclei

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By Julian Malchow, Carine F. Bourgeois, Golbarg M Roozbahani, P. L. Colosi, Attila Oravecz, Elena M. Sorokina, Wolfgang Pfeifer, Siamak Shokri, Yin Wei, Pascal Didier, Marcello DeLuca, Gaurav Arya, László Tora, Melike Lakadamyali, Michael Poirier, Carlos Castro, P. L. Colosi
| Science Magazine Verified
Abstract DNA origami nanostructures (DOs) are promising tools for applications including drug delivery, biosensing, detecting biomolecules, and probing chromatin substructures. Targeting these nanodevices to mammalian cell nuclei could provide impactful approaches for probing, visualizing, and controlling biomolecular processes within live cells. We present an approach to deliver DOs into live-cell nuclei.
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Versatile computer-aided design of free-form DNA nanostructures and assemblies

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By Outi M. Tervo, Wolfgang Pfeifer
| Science Magazine Verified
Abstract Recent advances in structural DNA nanotechnology have been facilitated by design tools that continue to push the limits of structural complexity while simplifying an often-tedious design process. We recently introduced the software MagicDNA, which enables design of complex 3D DNA assemblies with many components; however, the design of structures with free-form features like vertices or curvature still required iterative design guided by simulation feedback and user intuition.
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Versatile Computer Aided Design of Freeform DNA Nanostructures and Assemblies

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By Wolfgang Pfeifer, Michael Poirier, Gaurav Arya, Carlos Castro
| BioRxiv
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