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Articles by Wolfram Windisch
Molecular Identification of Mycobacterium tuberculosis and Mycobacterium bovis in Vitreous Fluid Samples from a Patient with Presumed Isolated Ocular Tuberculosis Complicated by Antituberculous Drug Toxicity
Submitted: 10 October 2026 You are already at the latest version A clinical case of an ophthalmological presentation of a combined infection with Mycobacteria tuberculosis and bovis is presented. The case was characterized by several challenges, both on a diagnostic and also on a therapeutic level in a multimorbid patient with chronic lung disease and bladder carcinoma. The latter thereby was identified as the indirect source of the M.
Auswirkungen defizitärer Kommunikation bei chronisch progredienten Erkrankungen in der ambulanten und hospitalen Versorgung
In der ambulanten (d.h. prä- und posthospitalen) und hospitalen Versorgung von Patienten mit chronisch progredienten Erkrankungen, wie z.B. der chronisch obstruktiven Lungenerkrankung (COPD) bzw. idiopathischen Lungenfibrose (IPF) bestehen sektorübergreifend schwerwiegende Kommunikationsdefizite vor allem bzgl. „Advanced Care Planning“ und der palliativmedizinischen Behandlung. Strategien zur Vermeidung intensivmedizinischer Überversorgung sind erforderlich[1].
Strategien zur Verbesserung der defizitären Kommunikation bei progredienten Erkrankungen bezogen auf die ambulanten und hospitalen Sektoren
In der Behandlung von Patienten mit progredienten Erkrankungen wie z.B. der COPD bzw. idiopathischen Lungenfibrose bestehen sektorübergreifend deutliche Kommunikationsdefizite. Maßnahmen zur verbesserten Kommunikation beinhalten „Advance Care Planning“, Ermittlung des Patientenwillens, frühe palliativmedizinische Versorgung und Vermeidung von nicht indizierter Hospitalisation, intensivmedizinischer und poststationärer Überversorgung wie z.B. außerklinische invasive Langzeitbeatmung[1].
Epidemiology of Neuralgic Amyotrophy-A Retrospective Analysis of Data From a Large German Health Insurance Company
1 Introduction Neuralgic amyotrophy (NA, Parsonage–Turner syndrome) is a common, underdiagnosed, multifocal autoimmune inflammatory disease that predominantly affects proximal nerve segments of the shoulder girdle. The classic clinical course begins with pronounced shoulder pain, followed by paresis within hours to days, particularly of the shoulder girdle muscles.
Targeting daytime normocapnia with nocturnal NIV in chronic hypercapnic COPD: the new paradigm?
Chronic obstructive pulmonary disease Targeting daytime normocapnia with nocturnal NIV in chronic hypercapnic COPD: the new paradigm? Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Noninvasive Ventilation in COPD-Pressure Matters
Noninvasive Ventilation in COPD—Pressure Matters Effect of Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in COPD Zujin Luo, MD; Yichong Li, PhD; Wenjun Li, MD; Ying Li, MD; Qingrong Nie, MD; Yu Shi, PhD; Juan Wang, BSN; Qiuling Ji, MD; Xuefeng Han, MD; Sijie Liu, MD; Dongmei Li, MD; ShaSha Wang, MD; Zhijun Li, MD; Dong Jia, MD; Huiqing Ge, MD; Peifeng Xu, BSc; Zhijun Feng, MD; Fengjie Li, MD; Fucheng An, MD; Na Tai, MD; Lili Yue, MD; Hongwei Xie, MD;...
A clinical phenotype of VEXAS syndrome with pleural effusion, infiltrates, and systemic inflammation in a 76-year-old patient: a case report - Journal of Medical Case Reports
VEXAS Syndrome (vacuoles, E1-ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic), first described in 2020, is a severe systemic inflammatory disease with a mutation in the UBA1 gene on the X chromosome in haemopoietic stem cells and is restricted to myeloid and erythroid cells in the periphery [1].
Long-term oxygen therapy in COPD: what is the evidence?
Thomas L Petty was the founder of modern long-term oxygen therapy (LTOT).In 1967, Petty's group published the seminal study of six patients with severe chronic airway obstruction, in whom LTOT improved clinical status, exercise capacity, secondary erythrocythemia, and pulmonary hypertension.Notably, all patients had severe hypoxaemia (partial pressure of oxygen [PaO] 41·5–46·5 mm Hg) and four patients were severely hypercapnic (partial pressure of carbon dioxide [PaCO] 55·0–61·5 mm Hg).
Home Non-Invasive Positive Pressure Ventilation in Chronic Obstructive Pulmonary Disease: Why, Who, and How?
Introduction – Why? Pathophysiologic Background of Chronic Ventilatory Failure Chronic obstructive pulmonary disease (COPD) is one of the most prevalent chronic diseases in Western countries. The disease progresses variably and can result in respiratory failure. Type I respiratory failure with severe hypoxaemia can be qualifying for Long-term oxygen treatment (LTOT). Therapeutic effects of LTOT are improved dyspnoea, exercise tolerance, and health-related quality of life (HRQL) [1].
Nasal versus oronasal masks for home non-invasive ventilation in patients with chronic hypercapnia: a systematic review and individual participant data meta-analysis
Nasal versus oronasal masks for home non-invasive ventilation in patients with chronic hypercapnia: a systematic review and individual participant data meta-analysis http://orcid.org/0000-0001-8414-3110Marius Lebret1, Antoine Léotard2, http://orcid.org/0000-0003-3832-2358Jean Louis Pépin3, Wolfram Windisch4,5,6, Emelie Ekkernkamp7, http://orcid.org/0000-0003-4262-0921Mercedes Pallero8,9, http://orcid.org/0000-0002-7220-6142M-Ángeles Sánchez-Quiroga10, Nicholas Hart11, Julia L Kelly12,...
Nasal versus oronasal masks for home non-invasive ventilation in patients with chronic hypercapnia: a systematic review and individual participant data meta-analysis
Nasal versus oronasal masks for home non-invasive ventilation in patients with chronic hypercapnia: a systematic review and individual participant data meta-analysis http://orcid.org/0000-0001-8414-3110Marius Lebret1, Antoine Léotard2, http://orcid.org/0000-0003-3832-2358Jean Louis Pépin3, Wolfram Windisch4,5,6, Emelie Ekkernkamp7, http://orcid.org/0000-0003-4262-0921Mercedes Pallero8,9, http://orcid.org/0000-0002-7220-6142M-Ángeles Sánchez-Quiroga10, Nicholas Hart11, Julia L Kelly12,...
Major differences in ICU admissions during the first and second COVID-19 wave in Germany
Several treatment options for patients with COVID-19 have been established since then. Corticosteroid treatment has been established for severely ill patients 2 Group RC Horby P Lim WS et al. Dexamethasone in hospitalized patients with COVID-19—preliminary report. The mortality of mechanically ventilated patients with COVID-19 in German intensive care units (ICUs) during the first wave of the pandemic was reported to be 53%., 3 Sterne JAC Murthy S Diaz JV et al.
Defining “stable chronic hypercapnia” in patients with COPD: the physiological perspective
Defining “stable chronic hypercapnia” in patients with COPD: the physiological perspective Begum Ergan, Raffaele Scala, Wolfram Windisch European Respiratory Journal Feb 2020, 55 (2) 1902365; DOI: 10.1183/13993003.02365-2019
Don't forget about neuromuscular disorders!
AbstractIn patients with NMD, ineffective coughing, recurrent aspiration and airway infections, respiratory failure and home mechanical ventilation require the expertise of respiratory physicians. Therefore, we should not forget about neuromuscular disorders! http://ow.ly/UeEA30lFMxnRespiratory medicine ostensibly targets diseases of the airways and the lungs, while respiratory problems arising from other entities are suggested to only play a minor role in this branch of medicine.
Long-term volume-targeted pressure-controlled ventilation: sense or nonsense?
Long-term volume-targeted pressure-controlled ventilation: sense or nonsense? Maria Paola Arellano-Maric, Cesare Gregoretti, Marieke Duivermann, Wolfram Windisch European Respiratory Journal Jun 2017, 49 (6) 1602193; DOI: 10.1183/13993003.02193-2016
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