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Wonyoung Jo

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Immune Mechanisms of Viral, Autoimmune, and Immune Checkpoint Inhibitor‐Associated Myocarditis

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By Vivian Z. Sun, Wonyoung Jo, Immunology Johns Hopkins
| Wiley Online Library Verified
1 Introduction Myocarditis is a heterogeneous inflammatory disease affecting the myocardium, the muscular middle layer of the heart wall composed primarily of contractile cardiac myocytes [1, 2]. Clinically, myocarditis presents with a wide spectrum of manifestations, ranging from asymptomatic or mild, self-limiting cases to fulminant disease characterized by acute heart failure, arrhythmias, or sudden cardiac death [3, 4].
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