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Articles

Disrupted cerebellar interactions in the cerebellar-thalamo-cortical triple network model across risk states and first-episode psychosis

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By Minji Ha, Inkyung Park, Hyungyou Park, Taekwan Kim, Wu Hwang, Jiseon Jang, Minah Kim, Jun Soo Kwon
| Nature Verified
Abstract Cerebellar dysconnectivity has been repeatedly linked to psychosis and is often accompanied by disruptions in thalamic and cortical regions. These disturbances are broadly consistent with the triple network model, which conceptualizes psychopathology as arising from abnormal interactions among the salience (SAL), default mode (DMN), and executive control (ECN) networks.
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Reduced cortical gyrification in the posteromedial cortex in unaffected relatives of schizophrenia patients with high genetic loading

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By Minah Kim, Wu Hwang, Inkyung Park, Yoo Bin Kwak
| Nature Verified
Abstract Although abnormal cortical gyrification has been consistently reported in patients with schizophrenia, whether gyrification abnormalities reflect a genetic risk for the disorder remains unknown. This study investigated differences in cortical gyrification between unaffected relatives (URs) with high genetic loading for schizophrenia and healthy controls (HCs) to identify potential genetic vulnerability markers.
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