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Wynton D. McClary on Muck Rack

Wynton D. McClary

As seen in: Nature, BioRxiv
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Articles

Intranasal replicon vaccine establishes mucosal immunity and protects against H5N1 and H7N9 influenza - Nature Communications

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By Ethan Lo, Eduard Melief, Wynton D. McClary
| Nature Verified
Abstract Seasonal and pandemic influenza viruses are continuous threats to human health, requiring rapid development of vaccines to multiple evolving viral strains. RNA vaccine technologies have the adaptability and manufacturability to facilitate pandemic preparedness but have limited flexibility in their route of administration, reducing the ability to establish local protective immune responses such as respiratory mucosal immunity.
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Development of an Intranasally- and Intramuscularly-Administrable Replicon Vaccine Efficacious Against H5N1 Influenza Virus

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By Madeleine F. Jennewein, Jasneet Singh, Wynton D. McClary, Devin S. Brandt
| BioRxiv
Abstract The risk of a respiratory viral pandemic is significant, including from the now widespread panzootic H5N1 influenza virus, highlighting the need for effective, stable, and inexpensive vaccine technologies that elicit strongly protective immunity.
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