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Introduction The renin-angiotensin system (RAS) is a peptidergic system with endocrine characteristics, well known for its pivotal role in the regulation of water and sodium homeostasis and blood pressure (Paul et al., 2006b). It involves the enzymatic conversion of angiotensinogen to angiotensin (Ang) I by renin. Through the classical pathway, Ang I may be converted to Ang II via the angiotensin-converting enzyme (ACE).
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