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19F-PCS measurements on proteins in live mammalian cells Pseudocontact shift (PCS) contains rich structural information of proteins in structural and chemical biology. Here, 19F-PCS is achieved in live mammalian cells via dual labelling of the target protein with a paramagnetic tag and a 19F-tag. About 0.1 ppm 19F-PCS can be determined over 20 Å from the paramagnetic center in live cells. This is the first obervation 19F-PCS in live mammalian cells.
Viruses harbored by bats and rodents, considered high-risk reservoirs, are no more likely to infect humans than viruses carried by other hosts, a study suggests.
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