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Xiajiao Nian on Muck Rack

Xiajiao Nian

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Articles

Gut microbiota–GABA axis dysregulation underlies polystyrene microplastic (PS-MP) neurotoxicity in rainbow trout: a role for oxidative stress and blood–brain barrier disruption

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By Fang Ma, Pan Zheng, Wenli Wang, Jiaxuan Dong, Xiangjun Zhou, Zhiyun Lin, Xiajiao Nian
| Nature Verified
Abstract Microplastics (MPs) threaten aquatic ecosystems and pose potential risks to organismal health through bioaccumulation in aquatic species. This study reveals that 14-day exposure to 5 μm polystyrene microplastics (PS-MPs) (500 μg/L) induces neurocognitive impairment in rainbow trout (Oncorhynchus mykiss), a globally consumed aquaculture species. MPs accumulated in brain and gut tissues, causing blood-brain barrier structural alterations, intestinal mucosal damage, and oxidative stress.
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